Literature summary for 3.2.2.23 extracted from

Song, J.; Yin, F.; Li, X.; Dong, N.; Zhu, Y.; Shao, Y.; Chen, B.; Jiang, W.; Li, C.Z.
Sensitive detection of formamidopyrimidine-DNA glycosylase activity based on target-induced self-primed rolling circle amplification and magnetic nanoprobes (2018), Analyst, 143, 1593-1598 .

Search for more literature for 3.2.2.23

Application

Application	Comment	Organism
analysis	simple and sensitive FPG activity assay using target-induced self-primed rolling circle amplification and magnetic nanoprobes. A 8-oxoguanine is positioned in duplex DNA containing a P-circle and P1, which together serve as a FPG substrate, rolling circle amplification template, and rolling circle amplification primer probe. The presence of FPG specifically binds and cleaves 8-oxoG containing duplex DNA, resulting in 5'-phosphoryl termini. The rolling circle amplification reaction produces an amount of long tandem-repeat DNA tiles with multiple recognizing regions for the modified DNA probes and biotin-modified DNA probes: A detection limit of 1.033 U/ml for FPG is obtained. FPG assays in human blood serum are also obtained using fluorescence and confocal laser scanning microscopy	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
commercial preparation	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
FPG	-	Homo sapiens

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Release 2023.1 (January 2023)